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| No. | Status | Study Title | Conditions | Interventions | Phase | Sponsor/Collaborators | Funder Type | Number Enrolled | Sex | Age | Locations |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1458 | Withdrawn | Evaluating the Effect of NT-I7, a Long Acting Interleukin-7, to Increase Lymphocyte Counts and Enhance Immune Clearance of SARS-CoV-2 (COVID-19) | SARS-CoV-2 | Drug: NT-I7 Drug: Placebo Procedure: Blood for research purposes Procedure: Blood for pharmacokinetic samples Procedure: Nasopharyngeal, oropharyngeal, or saliva swab Procedure: Blood for anti-drug antibody (ADA) |
Phase 1 | Washington University School of Medicine, NeoImmune Tech | OTHER | 0 | All | 18 Years | |
| 1457 | Active, not recruiting | Evaluating the Efficacy and Safety of Bromhexine Hydrochloride Tablets Combined With Standard Treatment/ Standard Treatment in Patients With Suspected and Mild Novel Coronavirus Pneumonia (COVID-19) | 2019-nCoV | Drug: Bromhexine Hydrochloride Tablets Drug: Arbidol Hydrochloride Granules Drug: Recombinant Human Interferon α2b Spray |
Not Applicable | Second Affiliated Hospital of Wenzhou Medical University, Wanbangde Pharmaceutical Group Co., LTD | OTHER | 18 | All | 18 Years ~ 80 Years | The Second AffIliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China |
| 1456 | Completed | Evaluating the Efficacy and Safety of Dolutegravir-Containing Versus Efavirenz-Containing Antiretroviral Therapy Regimens in HIV-1-Infected Pregnant Women and Their Infants | HIV Infections | Drug: Dolutegravir Drug: Emtricitabine/tenofovir alafenamide Drug: Emtricitabine/tenofovir disoproxil fumarate Drug: Efavirenz/emtricitabine/tenofovir disoproxil fumarate |
Phase 3 | National Institute of Allergy and Infectious Diseases (NIAID) | NIH | 643 | Female | 18 Years | Univ. of Florida Jacksonville NICHD CRS, Jacksonville, Florida, United States Pediatric Perinatal HIV Clinical Trials Unit CRS, Miami, Florida, United States Gaborone CRS, Gaborone, South-East District, Botswana Molepolole CRS, Gaborone, Botswana SOM Federal University Minas Gerais Brazil NICHD CRS, Belo Horizonte, Minas Gerais, Brazil Hospital Federal dos Servidores do Estado NICHD CRS, Rio De Janeiro, Brazil Instituto de Puericultura e Pediatria Martagao Gesteira - UFRJ NICHD CRS, Rio de Janeiro, Brazil Hosp. Geral De Nova Igaucu Brazil NICHD CRS, Rio de Janeiro, Brazil Byramjee Jeejeebhoy Medical College (BJMC) CRS, Pune, Maharashtra, India Soweto IMPAACT CRS, Johannesburg, Gauteng, South Africa Wits RHI Shandukani Research Centre CRS, Johannesburg, Gauteng, South Africa Umlazi CRS, Durban, Kwa Zulu Natal, South Africa Famcru Crs, Tygerberg, Western Cape Province, South Africa Kilimanjaro Christian Medical Centre (KCMC), Moshi, Tanzania Siriraj Hospital ,Mahidol University NICHD CRS, Bangkok, Bangkoknoi, Thailand Chiangrai Prachanukroh Hospital NICHD CRS, Chiang Mai, Thailand Chiang Mai University HIV Treatment (CMU HIV Treatment) CRS, Chiang Mai, Thailand Baylor-Uganda CRS, Kampala, Uganda Seke North CRS, Chitungwiza, Zimbabwe St Mary's CRS, Chitungwiza, Zimbabwe Harare Family Care CRS, Harare, Zimbabwe |
| 1455 | Not yet recruiting | Evaluating the Efficacy of Artesunate in Adults With Mild Symptoms of COVID-19 | Corona Virus Infection | Drug: Artemisinin / Artesunate Other: placebo |
Phase 2 | Princess Nourah Bint Abdulrahman University | OTHER | 22 | All | 18 Years ~ 60 Years | Princess Nourah Bint Abdulrahman Univeristy, Riyadh, Central, Saudi Arabia |
| 1454 | Recruiting | Evaluating the Efficacy of Convalescent Plasma in Symptomatic Outpatients Infected With COVID-19 | COVID-19 | Biological: CCP | Phase 2 | Metro Infectious Disease Consultants | OTHER | 150 | All | 18 Years | Metro Infectious Disease Consultants, Burr Ridge, Illinois, United States |
| 1453 | Terminated | Evaluating the Efficacy of Hydroxychloroquine and Azithromycin to Prevent Hospitalization or Death in Persons With COVID-19 | SARS-CoV 2 | Drug: Hydroxychloroquine (HCQ) Drug: Azithromycin (Azithro) Drug: Placebo for Hydroxychloroquine Drug: Placebo for Azithromycin |
Phase 2 | National Institute of Allergy and Infectious Diseases (NIAID), Teva Pharmaceuticals Industries LTD | NIH | 20 | All | 18 Years | Alabama CRS, Birmingham, Alabama, United States UCSD Antiviral Research Center CRS, San Diego, California, United States Harbor-UCLA CRS, Torrance, California, United States Whitman-Walker Health CRS, Washington, District of Columbia, United States Northwestern University CRS, Chicago, Illinois, United States Rush University CRS, Chicago, Illinois, United States Greensboro CRS, Greensboro, North Carolina, United States Cincinnati Clinical Research Site, Cincinnati, Ohio, United States University of Pittsburgh CRS, Pittsburgh, Pennsylvania, United States Trinity Health and Wellness Center CRS, Dallas, Texas, United States University of Washington AIDS CRS, Seattle, Washington, United States |
| 1452 | Completed | Evaluating the Infectivity, Safety, and Immunogenicity of a Single Dose of a Recombinant Live-Attenuated Respiratory Syncytial Virus Vaccine (D46/NS2/N/ΔM2-2-HindIII) in RSV-Seronegative Infants 6 to 24 Months of Age | Respiratory Syncytial Virus Infections | Biological: D46/NS2/N/ΔM2-2-HindIII Biological: Placebo |
Phase 1 | National Institute of Allergy and Infectious Diseases (NIAID) | NIH | 32 | All | 6 Months ~ 24 Months | Usc La Nichd Crs, Los Angeles, California, United States David Geffen School of Medicine at UCLA NICHD CRS, Los Angeles, California, United States Univ. of Colorado Denver NICHD CRS, Aurora, Colorado, United States Emory University School of Medicine NICHD CRS, Atlanta, Georgia, United States Rush Univ. Cook County Hosp. Chicago NICHD CRS, Chicago, Illinois, United States Lurie Children's Hospital of Chicago (LCH) CRS, Chicago, Illinois, United States Johns Hopkins University Center for Immunization Research, Baltimore, Maryland, United States Jacobi Med. Ctr. Bronx NICHD CRS, Bronx, New York, United States SUNY Stony Brook NICHD CRS, Stony Brook, New York, United States St. Jude Children's Research Hospital CRS, Memphis, Tennessee, United States |
